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Fig. 7 | Alzheimer's Research & Therapy

Fig. 7

From: Cerebrospinal fluid synaptosomal-associated protein 25 is a key player in synaptic degeneration in mild cognitive impairment and Alzheimer’s disease

Fig. 7

CSF SNAP-25 and SNAP-25/Aβ42 in relation to cognition and future cognitive change. MMSE and ADAS-cog at baseline (a, e) and over time (b, f) as a function of baseline CSF SNAP-25 in different diagnostic groups. MMSE and ADAS-cog at baseline (c, g) and over time (d, h) as a function of baseline SNAP-25/Aβ42 in different diagnostic groups. Biomarker levels and ratios are standardized to z scores. Aβ amyloid-β, AD Alzheimer’s disease, ADAS-cog Alzheimer’s Disease Assessment Scale cognitive subscale, CN cognitively normal, MMSE Mini-Mental State Examination, pMCI progressive mild cognitive impairment, sMCI stable mild cognitive impairment, SNAP-25 synaptosomal-associated protein 25

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