Fig. 4

CSF SNAP-25 levels and SNAP-25/Aβ42 ratio in relation to tau biomarkers. Correlations between CSF SNAP-25 levels (a) and SNAP-25/Aβ42 ratio (b) and t-tau in different diagnostic groups. Correlations between CSF SNAP-25 levels (c) and SNAP-25/Aβ42 ratio (d) and p-tau in different diagnostic groups. Aβ amyloid-β, AD Alzheimer’s disease, CN cognitively normal, P-tau phosphorylated tau, pMCI progressive mild cognitive impairment, sMCI stable mild cognitive impairment, SNAP-25 synaptosomal-associated protein 25, T-tau total tau