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Fig. 1 | Alzheimer's Research & Therapy

Fig. 1

From: Cerebrospinal fluid synaptosomal-associated protein 25 is a key player in synaptic degeneration in mild cognitive impairment and Alzheimer’s disease

Fig. 1

CSF SNAP-25 levels and SNAP-25/Aβ42 ratio in different diagnostic groups. CSF SNAP-25 levels (a) and SNAP-25/Aβ42 ratio (c) in different diagnostic groups. CSF SNAP-25 levels (b) and SNAP-25/Aβ42 ratio (d) in the healthy control subjects who progressed to MCI or AD (progressive healthy controls). Differences between groups were tested by multiple-variable linear regression, adjusted for age and sex. *p < 0.05, **p < 0.01, ***p < 0.0001. Aβ amyloid-β, AD Alzheimer’s disease, CN cognitively normal, pCN progressively cognitive normal, pMCI progressive mild cognitive impairment, sCN stably cognitive normal, sMCI stable mild cognitive impairment, SNAP-25 synaptosomal-associated protein 25

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