Fig. 1From: Cerebrospinal fluid soluble TREM2 levels in frontotemporal dementia differ by genetic and pathological subgroupComparison of CSF sTREM2 levels between groups and subgroups. Graphs show how CSF sTREM2 levels differ across (a) control and dementia (overall FTD, containing bvFTD and PPA) groups; (b) controls and clinical subgroups; (c) controls and genetic subgroups; and (d) controls and CSF biomarker-defined dementia subgroups (pathological subgroups). AD biomarker-negative dementia: CSF T-tau/Aβ42 ratio < 1.0; AD biomarker-positive dementia: CSF T-tau/Aβ42 ratio > 1.0. Horizontal bars show mean CSF sTREM2 levels and upper and lower 95% CIs for each group. *P < 0.05, **P < 0.01. Aβ42 β-Amyloid 1–42, AD Alzheimer’s disease, bvFTD Behavioural variant frontotemporal dementia, C9orf72 Chromosome 9 open reading frame 72 gene, FTD Frontotemporal dementia, CSF Cerebrospinal fluid, GRN Progranulin gene, lvPPA Logopenic variant primary progressive aphasia, MAPT Microtubule-associated protein tau gene, nfvPPA Non-fluent variant primary progressive aphasia, PPA-NOS Primary progressive aphasia not otherwise specified, sTREM2 Soluble triggering receptor expressed on myeloid cells 2, svPPA Semantic variant primary progressive aphasia, T-tau Total tauBack to article page