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Fig. 2 | Alzheimer's Research & Therapy

Fig. 2

From: Plasma neurofilament light as a potential biomarker of neurodegeneration in Alzheimer’s disease

Fig. 2

Unadjusted neurofilament light chain (NfL) concentrations in the three diagnostic categories. A borderline insignificant (p = 0.11 after Scheffe correction) tendency was observed towards higher concentrations in Alzheimer’s disease dementia (ADD) compared with mild cognitive impairment Alzheimer’s disease (MCI-AD). The green horizontal line represents the cutoff at the maximized Youden index (25.7 pg/mL), leading to the unadjusted diagnostic accuracy of 82% in the setting of controls versus AD (MCI-AD and ADD). *p < 0.05

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