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Table 1 Demographics and key characteristics of the in vivo population

From: In vivo quantification of neurofibrillary tangles with [18F]MK-6240

 

Young CN individuals

Elderly CN individuals

MCI patients

AD patients

N

3

6

3

4

Age (years), mean (SD)

22.3 (1.5)

67.8 (8.5)

69 (3.4)

60.7 (6)

Male, n (%)

2 (67)

5 (83)

2 (67)

3 (75)

MMSE, mean (SD)

30 (0)

29.5 (0.5)

25 (2.6)

17.3 (5.8)

APOE ε4, n (%)

0 (0)

4 (67)

1 (33)

2 (50)

Amyloid-PET positive, n (%)

0 (0)

1 (17)

3 (100)

4 (100)

  1. AD Alzheimer’s disease, CN cognitively healthy, MCI mild cognitive impairment, MMSE Mini-Mental State Examination, PET positron emission tomography, SD standard deviation