Table 5 MMRM-estimated cognitive composite score change from baseline results
From: Cognitive composite score association with Alzheimer’s disease plaque and tangle pathology
Δ from baseline | p value | Δ from low group | p value | |
|---|---|---|---|---|
Low CERAD | − 1.80 (−3.79, 0.19) | 0.08 | NA | NA |
High CERAD | −4.54 (−5.80, −3.28) | < 0.001 | −2.74 (−5.01, − 0.47) | 0.02 |
Low Braak | −3.30 (−5.38, −1.23) | 0.002 | NA | NA |
High Braak | −3.99 (−5.25, −2.74) | < 0.001 | −0.69 (−3.03, 1.66) | 0.56 |
Low CERAD/low Braak | −4.34 (−7.09, −1.58) | 0.002 | NA | NA |
Intermediate | −0.49 (−2.52, 1.54) | 0.64 | 3.85 (0.55, 7.15) | 0.02 |
High CERAD/high Braak | −5.12 (−6.48, −3.76) | < 0.001 | −0.78 (−3.81, 2.24) | 0.61 |