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Table 4 Effect of Aβ on MMSE scores over time by diagnostic group

From: The EMIF-AD Multimodal Biomarker Discovery study: design, methods and cohort characteristics

Diagnosis n Baseline p value Slope p value
NC 482 − 0.35 ± 0.20 0.170 − 0.60 ± 0.13 < 0.001
MCI 459 − 1.56 ± 0.24 < 0.001 − 0.60 ± 0.14 < 0.001
AD dementia 162 − 0.05 ± 1.05 0.965 − 0.21 ± 0.64 0.742
  1. Numbers are linear mixed-model coefficients ± standard error, relative to the Aβ– group, adjusted for age, gender and years of education
  2. amyloid-beta, AD Alzheimer’s disease, MCI mild cognitive impairment, MMSE Mini Mental State Examination, NC normal cognition