Plasma amyloid-β levels, cerebral atrophy and risk of dementia: a population-based study

Table 3 Association of amyloid-β levels with incident dementia and its subtypes

Plasma Aβ levels (per SD decrease)	Incident dementia (n = 79) HR (95% CI)^a	Alzheimer’s dementia (n = 64) HR (95% CI)^a	Vascular dementia (n = 15) HR (95% CI)^a
Aβ_1–38	1.33 (1.01–1.89) ^b	1.39 (1.00–2.16) ^b	1.20 (0.49–2.96)
Aβ_1–40	0.99 (0.69–1.43)	0.95 (0.60–1.49)	0.74 (0.31–1.79)
Aβ_1–42	1.27 (1.02–1.58) ^b	1.35 (1.05–1.75) ^b	1.05 (0.61–1.79)
Aβ_1–40/Aβ_1–42 ratio	0.92 (0.64–1.32)	0.97 (0.64–1.49)	1.30 (0.54–3.11)

Abbreviations: Aβ amyloid-β, SD standard deviation, HR hazard ratio, CI confidence interval
^aAdjusted for age, sex, education, mean arterial blood pressure, total cholesterol, diabetes, apolipoprotein ε4 carrier status, smoking and other Aβ levels
^bSignificant at p <0.05

ISSN: 1758-9193