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Fig. 5 | Alzheimer's Research & Therapy

Fig. 5

From: Single-word comprehension deficits in the nonfluent variant of primary progressive aphasia

Fig. 5

Elevated [18F]-THK5351-binding patterns. Elevated [18F]-THK5351 binding on partial volume corrected SUVR images, statistically contrasted using a voxel-wise ANOVA with age and gender as covariates, depicted by a one-sided t contrast on an MNI template brain rendering and on coronal slices in a mixed variant (MV) PPA compared with healthy controls (HC), b nonfluent/agrammatic variant (NFV) pure PPA compared with HC, c MV compared with NFV pure, d NFV pure compared with MV, e MV compared with semantic variant (SV), f SV compared with MV, g MV compared with logopenic variant (LV), and h LV compared with MV. The significance threshold was set at voxel-level uncorrected P < 0.001 with cluster-level family wise error (FWE)-corrected threshold P < 0.05. L left, R right

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