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Table 2 Fresh frozen cases used for immunoprecipitation

From: Immunotherapy to improve cognition and reduce pathological species in an Alzheimer’s disease mouse model

Case

Sex

Age (years)

ABC

Neuropathological diagnosis

Cognitively normal control 1

F

95

A0,B0,C0

lacunar microinfarcts, dystrophic calcification in hippocampus

Cognitively normal control 2

M

79

A1,B1,C1

ADRC/small vessel disease

Cognitively normal control 3

M

90

A1,B1,C1

ADRC

AD1

F

91

A3,B3,C3

AD

AD2

M

76

A3,B3,C3

AD/CAA

AD3

F

83

A3,B3,C3

AD

  1. ABC score and neuropathological diagnosis was determined as previously published [31] and reported by a board-certified neuropathologist
  2. AD Alzheimer’s disease, ADRC Alzheimer’s disease-related changes, CAA cerebral amyloid angiopathy, F female, M male