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Table 1 Events prior to 1st January 2016 that potentially affected prescription rates

From: What is the impact of regulatory guidance and expiry of drug patents on dementia drug prescriptions in England? A trend analysis in the Clinical Practice Research Datalink

Event date

Event

May 1997

Donepezil first recorded in CPRD

September 1998

Rivastigmine first recorded in CPRD

January 2001

Galantamine first recorded in CPRD and first NICE guidance released

December 2002

Memantine first recorded in CPRD

November 2006

NICE recommended restricting drug access

September 2007

QOF revised to include dementia

February 2009

First National Dementia Strategy launched

March 2011

NICE removed recommendation restricting drug access

January 2012

Galantamine patent expired

February 2012

Donepezil patent expired

May 2012

Prime Minister’s Dementia Challenge launched

July 2012

Rivastigmine patent expired

April 2014

Memantine patent expired

February 2015

Prime Minister’s Challenge on Dementia 2020 launched

  1. CPRD Clinical Practice Research Datalink, NICE National Institute for Health and Care Excellence, QOF Quality and Outcomes Framework