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Table 2 Sample characteristics

From: White matter microstructure is altered in cognitively normal middle-aged APOE-ε4 homozygotes

 

Total sample (N = 532)

NC (n = 257)

HE (n = 207)

HO (n = 68)

Inferential statistics

 

Mean

SD

Mean

SD

Mean

SD

Mean

SD

 

Age, years

58.13

7.46

58.52

7.62

58.71

7.41

54.94

6.22

F = 7.37; p < 0.01

Education, years

13.61

3.54

13.61

3.60

13.59

3.52

13.38

3.48

F = 0.19; p = 0.83

MMSE score

29.06

1.05

29.00

1.12

29.02

1.11

29.26

0.78

F = 1.45; p = 0.24

TFRa

16.46

5.16

16.32

5.20

16.24

5.09

17.73

5.16

F = 2.25; p = 0.11

TPRa

24.13

4.48

23.83

4.85

24.16

4.19

25.19

3.71

F = 2.36; p = 0.10

Males/females, n

211/321

92/165

94/113

25/43

χ2 = 4.79; p = 0.09

  1. Abbreviations: NC Noncarriers; HE ε4-Heterozygous; HO ε4-Homozygous; MMSE Mini Mental State Examination; TPR Total paired recall; TFR Total free recall
  2. aFull evaluation of cognitive performance was not available for 16 subjects