Fig. 5
From: White matter microstructure is altered in cognitively normal middle-aged APOE-ε4 homozygotes
Effect of aging and APOE genotype on diffusion parameters (in seconds per mm2) on significant voxels in the additive contrast. Left: Scatterplots of regional diffusivity across subjects (MD, RD, and AxD from top to bottom) regressed by age (solid lines). Right: Box plots based on genotype groups (ε4 homozygotes [HO], ε4 heterozygotes [HT], and noncarriers [NC] from left to right). Asterisks depict significance after a post hoc t test (p < 0.001, uncorrected)