Table 3 Clinical and neuropsychological features of the MCI sample grouped according to the evidence (i.e., Aβ+ MCI) or the absence (i.e., Aβ- MCI) of amyloid pathology by amyloid-PET and/or CSF imaging. Amyloid pathology information was available in 26/30 MCI subjects. Values are shown as mean ± standard deviation

Female/Male ratio

8/7

11/1

p<0.05

Age in years

73.5±5.4

75.3±4.5

p=0.4

Years of education

9.2±4.8

11.1±4.9

p=0.3

Disease duration in months

30.3±16

50.3±29

p<0.05

 Mini Mental State Examination (cut-off = 24)

25±3.9

26.5±2.9

p= 0.31

 Token test (cut-off = 26.25)

30.8±4.3

30.7±2

p=0.9

 Phonemic fluency (cut-off = 16)

24.1±12.2

20±7.4

p=0.34

 Semantic fluency (cut-off = 24)

28.8±10.5

27.1±5.7

p=0.64

 Digit Span (cut-off = 3.5)

5.23±1.3

5.5±1.1

p=0.66

 Corsi Span (cut-off = 3.5)

4.7±0.8

4.3±0.7

p=0.25

 Rey Auditory Verbal Learning Test immediate recall (cut-off = 28.5)

19.17±3.7

20.3±5.1

p=0.55

 Rey Auditory Verbal Learning Test delayed recall (cut-off = 4.68)

1.42±1.9

1.22±1.5

p=0.80

 Rey-Osterrieth Complex Figure recall (cut-off = 9.46)

6.25±3.1

6.25±5.2

p=1

 Rey-Osterrieth Complex Figure copy (cut-off = 28.87)

22.6±9

28.64±6.1

p=0.075

 Attentive Matrices (cut-off = 30)

43.85±7

45.18±10.7

p=0.72

 Raven Matrices (cut-off = 17.5)

24.9±7.1

22.73±6.1

p=0.52