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Table 2 Demographic data, clinical features and biomarker findings in each enrolled patient. The table shows patients’ findings according to the biomarkers (n. 26 with FDG-PET data and amyloid measures, either by amyloid-PET study or CSF assessment; n.4 with FDG-PET data)

From: A biomarker study in long-lasting amnestic mild cognitive impairment

  Gender Age Education MMSE at the first evaluation Diagnosis at the first evaluation Disease duration at the first evaluation MMSE at the follow-up Diagnosis at the follow-up Disease duration at the follow-up FDG-PET pattern Amyloid-PET neocortical SUVr values CSF Aβ42 CSF t-Tau CSF p-Tau t-Tau/ Aβ42 Ratio
#1 F 79 17 26 s-aMCI 26 24 s-aMCI 81 C 1.38 752 222 45 0.29
#2 M 77 6 28 s-aMCI 48 27 s-aMCI 145 C 1.16 957 243 35 0.25
#3 M 71 13 29 m-aMCI 108 28 m-aMCI 163 B 1.15 630 122 30 0.19
#4 M 83 17 24 m-aMCI 36 22 m-aMCI 118 C 1.09 1000 505 71 0.50
#5 M 75 5 23 m-aMCI 60 25 m-aMCI 119 C 1.18 720 174 35 0.24
#6 M 72 13 27 s-aMCI 72 28 s-aMCI 127 B 1.63 255 352 82 1.38
#7 M 79 18 25 s-aMCI 72 23 m-aMCI 115 C 1.90 252 293 73 1.16
#8 M 68 8 29 s-aMCI 36 25 m-aMCI 91 B 1.44 400 275 52 0.68
#9 M 70 5 25 s-aMCI 48 26 m-aMCI 115 B 1.21 411 638 102 1.55
#10 M 84 13 28 m-aMCI 96 22 m-aMCI 151 C 1.59 596 171 39 0.28
#11 M 77 11 25 s-aMCI 48 25 s-aMCI 103 B 1.66 - - - -
#12 M 69 8 27 s-aMCI 36 26 s-aMCI 83 B 1.69 - - - -
#13 F 71 12 24 s-aMCI 24 25 s-aMCI 79 C 1.83 - - - -
#14 F 69 8 29 m-aMCI 24 22 m-aMCI 79 C 1.71 - - - -
#15 M 77 3 24 m-aMCI 36 23 m-aMCI 91 C 1.19 - - - -
#16 F 76 5 27 m-aMCI 60 26 m-aMCI 115 C 1.59 - - - -
#17 M 71 18 28 s-aMCI 24 28 s-aMCI 79 A - 742 259 42 0.34
#18 F 69 17 27 s-aMCI 108 26 m-aMCI 175 A - 270 339 70 1.25
#19 F 65 8 28 s-aMCI 24 27 m-aMCI 85 B - 497 489 105 0.98
#20 F 68 5 25 m-aMCI 60 23 m-aMCI 118 B - 365 343 59 0.94
#21 M 76 8 27 m-aMCI 18 26 m-aMCI 73 B - 734 268 45 0.36
#22 F 80 10 26 m-aMCI 24 21 m-aMCI 91 A - 355 763 108 2.15
#23 M 78 13 29 m-aMCI 24 27 m-aMCI 73 C - 1010 379 87 0.37
#24 M 71 8 28 m-aMCI 24 26 m-aMCI 79 B - 308 886 134 2.87
#25 M 77 13 29 m-aMCI 60 28 m-aMCI 123 C - 847 379 84 0.45
#26 F 75 12 24 m-aMCI 24 23 m-aMCI 79 A - 454 244 48 0.54
#27 F 73 5 25 s-aMCI 50 25 s-aMCI 79 C - - - - -
#28 M 79 13 28 s-aMCI 120 27 s-aMCI 83 C - - - - -
#29 F 69 13 29 s-aMCI 60 27 m-aMCI 87 C - - - - -
#30 F 76 5 21 m-aMCI 52 21 m-aMCI 85 B - - - - -
  1. MMSE Mini Mental State Examination; CSF cerebrospinal fluid; Aβ42 β Amyloid (1-42) protein; t-Tau total tau; p-Tau phosphorylated tau; M male; F female; s-aMCI single-domain amnestic Mild Cognitive Impairment; m-aMCI multiple domain amnestic Mild Cognitive Impairment; FDG-PET pattern A selective hypometabolism of medial temporal lobe structures (hippocampus and/or hippocampal structures); FDG-PET pattern B hypometabolism of medial temporal lobe structures and posterior cingulate cortex; FDG-PET pattern C extensive hypometabolism involving medial temporal lobe structures and other fronto-limbic structures