Skip to main content

Table 6 Whole-brain voxel-based analyses of 18F-fluorodeoxyglucose positron emission tomographic images in SPM8

From: Metabolic correlates of reserve and resilience in MCI due to Alzheimer's Disease (AD)

 

Cluster level

Peak level

Cluster extent

Corrected p value

Cortical region

Maximum z-score

 

Talairach coordinates

 

Cortical region

BA

Comparison between CTR and poorly educated patients with MCI

 983

0.005

L-parietal

6.83

− 57

− 38

50

Inferior parietal lobule

40

  

L-temporal

4.36

− 44

4

− 37

Middle temporal gyrus

38

Comparison between CTR and patients with MCI with an average education level

 300

0.008

L-parietal

6.2

− 54

− 33

49

Inferior parietal lobule

40

 278

0.005

R-parietal

65.8

50

− 45

29

Inferior parietal lobule

40

Comparison between CTR and highly educated patients with MCI

 14,247

0.001

L-parietal

6.83

− 12

− 47

34

Precuneus

31

  

R-parietal

5.00

10

− 64

47

Precuneus

7

  

L-parietal

4.10

− 61

− 53

34

Supramarginal gyrus

40

  

R-temporal

3.55

50

− 13

− 25

Fusiform gyrus

20

  

L-temporal

4.08

− 65

− 44

10

Superior temporal gyrus

22

  

L-parietal

4.01

− 53

− 37

51

Inferior parietal lobule

40

  

L-limbic

3.73

− 18

− 58

16

Posterior cingulate gyrus

30

Comparison between CTR and exceptionally educated patients with MCI

 998

0.001

L-parietal

6.53

− 12

− 47

34

Precuneus

31

  

L-parietal

5.08

− 61

− 53

34

Supramarginal gyrus

40

  1. Abbreviations: BA Brodmann area, CTR Healthy volunteer control subjects, MCI Mild cognitive impairment
  2. p < 0.05 corrected for multiple comparisons with family-wise error correction option at both peak and cluster levels was accepted as statistically significant. In the “cluster level” section at left, the corrected p value and the brain lobe with hypometabolism are reported. In the “peak level” section at right, the z-score and peak coordinates, as well as the corresponding cortical region and BA, are reported