Skip to main content

Advertisement

Table 6 Whole-brain voxel-based analyses of 18F-fluorodeoxyglucose positron emission tomographic images in SPM8

From: Metabolic correlates of reserve and resilience in MCI due to Alzheimer's Disease (AD)

  Cluster level Peak level
Cluster extent Corrected p value Cortical region Maximum z-score   Talairach coordinates   Cortical region BA
Comparison between CTR and poorly educated patients with MCI
 983 0.005 L-parietal 6.83 − 57 − 38 50 Inferior parietal lobule 40
   L-temporal 4.36 − 44 4 − 37 Middle temporal gyrus 38
Comparison between CTR and patients with MCI with an average education level
 300 0.008 L-parietal 6.2 − 54 − 33 49 Inferior parietal lobule 40
 278 0.005 R-parietal 65.8 50 − 45 29 Inferior parietal lobule 40
Comparison between CTR and highly educated patients with MCI
 14,247 0.001 L-parietal 6.83 − 12 − 47 34 Precuneus 31
   R-parietal 5.00 10 − 64 47 Precuneus 7
   L-parietal 4.10 − 61 − 53 34 Supramarginal gyrus 40
   R-temporal 3.55 50 − 13 − 25 Fusiform gyrus 20
   L-temporal 4.08 − 65 − 44 10 Superior temporal gyrus 22
   L-parietal 4.01 − 53 − 37 51 Inferior parietal lobule 40
   L-limbic 3.73 − 18 − 58 16 Posterior cingulate gyrus 30
Comparison between CTR and exceptionally educated patients with MCI
 998 0.001 L-parietal 6.53 − 12 − 47 34 Precuneus 31
   L-parietal 5.08 − 61 − 53 34 Supramarginal gyrus 40
  1. Abbreviations: BA Brodmann area, CTR Healthy volunteer control subjects, MCI Mild cognitive impairment
  2. p < 0.05 corrected for multiple comparisons with family-wise error correction option at both peak and cluster levels was accepted as statistically significant. In the “cluster level” section at left, the corrected p value and the brain lobe with hypometabolism are reported. In the “peak level” section at right, the z-score and peak coordinates, as well as the corresponding cortical region and BA, are reported