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Table 1 Demographic and main clinical characteristics of the study groups

From: Metabolic correlates of reserve and resilience in MCI due to Alzheimer's Disease (AD)

Characteristics CTR (n = 48) MCI-AD (n = 94) AMY+ MCI (n = 39)
Age, years 69.0 ± 9.7 75.3 ± 5.7 74.2 ± 6.4
Sex
 Male 12 42 21
 Female 36 52 18
Education, years 10.0 ± 4.0 10.1 ± 2.0 10.5 ± 4.1
ApoE ε4 allele statusa N/A N/A 14/22b
Baseline NPS
 MMSE 29.0 ± 0.9 26.0 ± 1.1 27.1 ± 2.6
Follow-up duration, years 3.2 ± 1.5 2.3 ± 1.0
Conversion time, months 23.2 ± 16.2 (range 6–98)
Follow-up MMSE score 22.3 ± 2.0 25.9 ± 3.4
ΔMMSE/year   − 1.5 ± 1.2 − 0.6 ± 0.4
  1. Abbreviations: AMY+ MCI Patients with mild cognitive impairment who had a positive result for a brain amyloidosis biomarker, ApoE Apolipoprotein E, CTR Healthy volunteer control subjects, MCI-AD Patients with mild cognitive impairment due to Alzheimer’s disease, MMSE Mini Mental State Examination, ΔMMSE Reduction in Mini Mental State Examination score, NPS Neuropsychology
  2. Data are presented as mean ± SD
  3. aEither as homozygous or heterozygous for ApoE ε4 allele
  4. bAvailable in 22 of 39 patients (3 of 22 homozygous and 11 of 22 heterozygous for ApoE ε4 allele) to date