Characteristic | EXPEDITION RCTs (EU population) | GERAS observational study | p value for unadjusted baseline comparison |
---|---|---|---|
Patients, N | 168 | 566 | |
Age (years) | 71.9 (7.4) | 77.3 (6.9) | < 0.001 |
Sex (female), n (%) | 85 (50.6) | 271 (47.9) | 0.83 |
Patient education (years) | 11.6 (3.9) | 11.1 (3.3) | 0.06 |
Time since AD diagnosis (years) | 1.7 (1.5) | 1.7 (2.0) | 0.90 |
AD treatment category, n (%) | < 0.001 | ||
AChEI only | 129 (76.8) | 411 (72.6) | |
Memantine only | 12 (7.1) | 41 (7.2) | |
AChEI + memantine | 19 (11.3) | 26 (4.6) | |
No AD treatment | 8 (4.8) | 88 (15.5) | |
MMSE score | 23.1 (2.0) | 23.3 (1.6) | 0.15 |
Caregivers, N | 168 | 566 | |
Age (years) | 64.2 (12.2) | 68.1 (11.6) | < 0.001 |
Sex (female), n (%) | 101 (60.5) | 387 (68.5) | 0.21 |
Caregiver is patient’s spouse, n (%) | 116 (69.5) | 399 (70.6) | 0.82 |
Caregiver is working for pay, n (%) | 57 (34.1) | 133 (23.5) | 0.04 |