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Table 1 Characteristics of subjects by final neuropathological diagnosis

From: Improving the identification of dementia with Lewy bodies in the context of an Alzheimer’s-type dementia

 

AD

DLB

Mixed AD+DLB

 

N = 19

N = 18

N = 22

Age at baseline (years)

76.8 (9.3)

71.0 (6.1)

70.5 (9.0)

F = (2,56) 3.4, P = 0.04

DLB vs AD, P = 0.03

DLB vs mixed, P = 0.87

AD vs mixed, P = 0.04

Age at death (years)

82.7 (9.4)

76.9 (5.3)

78.2 (8.8)

F = (2,56) 2.6, P = 0.08

DLB vs AD, P = 0.03

DLB vs mixed, P = 0.58

AD vs mixed, P = 0.16

Gender (male:female)

13:6

14:4

16:6

X = 0.41, df = 2, P = 0.82

Interval between baseline and death (years)

5.8 (2.5)

5.9 (1.9)

7.8 (2.6)

F = (2,56) 4.5, P = 0.015

DLB vs AD, P = 0.83

DLB vs mixed, P = 0.02

AD vs mixed, P = 0.02

Baseline MMSE

18.0 (7.5)

25.3 (2.7)

22.0 (3.9)

F = (2,52) 8.5, P = 0.001

DLB vs AD, P = 0.001

DLB vs mixed, P = 0.01

AD vs mixed, P = 0.04

Final MMSE

5.9 (7.8)

12.8 (6.9)

6.8 (9.4)

F = (2,53) 3.6, P = 0.04

DLB vs AD, P = 0.01

DLB vs mixed, P = 0.04

AD vs mixed, P = 0.75

Interval between last assessment and death (months)

20.9 (13.8)

25.4 (17.1)

35.9 (28.7)

F = (2,51) 2.5, P = 0.09

DLB vs AD, P = 0.40

DLB vs mixed, P = 0.19

AD vs mixed, P = 0.05

  1. AD Alzheimer’s disease, DLB dementia with Lewy bodies, MMSE Mini-Mental State Examination