Table 1 Characteristics of study subjects

Male sex, n (%)

6 (42.9)

6 (42.9)

20 (47.1%)

14 (60.9%)

Age, years

68.1 ± 2.9

69.3 ± 2.7

69.4 ± 10.9

68.6 ± 7.83

Education level, years

13.4 ± 0.6

7.5 ± 1.2^a

9.9 ± 1.46

8.3 ± 0.75

MMSE score

29.1 ± 0.2 (26-30)

16.6 ± 1.4 (6-24)^a

17.6 ± 7.0 ^a

15.3 ± 8.14^a

APOE ε4, n (%)

3 (23.1%)^b

10 (71.4%)^a

19 (54.3%)^a

10 (43.5%)^a

Folate, ng/ml

–

8.8 ± 0.7

9.72 ± 0.90

22.9 ± 3.12

Vitamin B₁₂, pg/ml

–

499.6 ± 59.1

489.2 ± 47.2

329.4 ± 77.5

TDP, nmol/L

117.1 ± 4.7

84.9 ± 7.1^a

101.3 ± 30.3^a

–

SUVR of FDG or PiB in frontal cortex

1.25 ± 0.030

1.10 ± 0.055^a

1.9 ± 0.5

1.04 ± 0.02^a1.9 ± 0.5

SUVR of FDG or PiB in temporal cortex

1.17 ± 0.028

0.95 ± 0.051^a

1.7 ± 0.5

1.05 ± 0.02^a2.00 ± 0.08

SUVR of FDG or PiB in parietal cortex

1.16 ± 0.031

0.97 ± 0.044^a

1.7 ± 0.4

0.92 ± 0.02^a1.96 ± 0.07