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Table 1 Baseline characteristics of patients with Alzheimer’s disease according to outcome

From: Disease-related determinants are associated with mortality in dementia due to Alzheimer’s disease

 

No. of patients

Alive (n = 403)

Died (n = 213)

p Value

Demographics

 Female sex, n (%)

616

218 (54)

91 (43)

0.007

 Age, years

616

66 ± 7

69 ± 9

0.000

APOE ε4 carrier, n (%)

562

250 (67)

119 (63)

0.280

 Years of education

616

11 ± 3

11 ± 3

0.675

 Years of complaints

611

3.2 ± 2.6

2.8 ± 2.0

0.066

 Years to outcome

616

5.3 ± 1.8

4.3 ± 2.1

0.000

 Activities of daily living (DAD)

372

83 ± 17

82 ± 17

0.450

Medical history

 Smoking, n (%)

599

185 (47)

98 (49)

0.640

 Hypertension, n (%)

616

127 (32)

77 (36)

0.245

 Hypercholesterolemia, n (%)

616

103 (26)

46 (22)

0.275

 Diabetes mellitus, n (%)

616

31 (8)

15 (7)

0.770

 Cardiovascular disease, n (%)

616

71 (18)

53 (25)

0.032

 No. of medications

616

2.0 ± 2.0

2.4 ± 2.1

0.062

  1. Abbreviations: APOE Apolipoprotein E, DAD Disability Assessment for Dementia (range 0–100)
  2. Years to outcome: in case of alive, follow-up duration; in case of died, duration to death
  3. Data are presented as mean ± SD unless otherwise specified. Group differences were calculated using Student’s t test for continuous variables. For categorical variables, the chi-square test was used