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Table 1 Baseline characteristics of patients with Alzheimer’s disease according to outcome

From: Disease-related determinants are associated with mortality in dementia due to Alzheimer’s disease

  No. of patients Alive (n = 403) Died (n = 213) p Value
Demographics
 Female sex, n (%) 616 218 (54) 91 (43) 0.007
 Age, years 616 66 ± 7 69 ± 9 0.000
APOE ε4 carrier, n (%) 562 250 (67) 119 (63) 0.280
 Years of education 616 11 ± 3 11 ± 3 0.675
 Years of complaints 611 3.2 ± 2.6 2.8 ± 2.0 0.066
 Years to outcome 616 5.3 ± 1.8 4.3 ± 2.1 0.000
 Activities of daily living (DAD) 372 83 ± 17 82 ± 17 0.450
Medical history
 Smoking, n (%) 599 185 (47) 98 (49) 0.640
 Hypertension, n (%) 616 127 (32) 77 (36) 0.245
 Hypercholesterolemia, n (%) 616 103 (26) 46 (22) 0.275
 Diabetes mellitus, n (%) 616 31 (8) 15 (7) 0.770
 Cardiovascular disease, n (%) 616 71 (18) 53 (25) 0.032
 No. of medications 616 2.0 ± 2.0 2.4 ± 2.1 0.062
  1. Abbreviations: APOE Apolipoprotein E, DAD Disability Assessment for Dementia (range 0–100)
  2. Years to outcome: in case of alive, follow-up duration; in case of died, duration to death
  3. Data are presented as mean ± SD unless otherwise specified. Group differences were calculated using Student’s t test for continuous variables. For categorical variables, the chi-square test was used