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Table 3 Interactions of Bcl-2 genotypes with pre-defined seed

From: Associations of Bcl-2 rs956572 genotype groups in the structural covariance network in early-stage Alzheimer’s disease

Seed Peak regions   Stereotaxic coordinates Extent Max T P-value
Side x y z    
Right entorhinal seed (Medial Temporal Subsystem of DMN)
 G- carriers < AA Mid-occipital R 39 -66 24 288 4.34 <0.0001
Mid-Frontal R 29 29 34 869 3.98 <0.0001
Superior Frontal R 12 14 57 255 3.97 <0.0001
Left posterior cingulate seed (Medline Subsystem of DMN)
 G-carriers > AA Cerebellum area6 L -33 -57 -21 928 4.41 <0.0001
Cerebellum area6 L -23 -55 -20 1137 4.32 <0.0001
 G-carriers < AA Sub-lobar L -23 8 13 596 4.77 <0.0001
Right frontoinsular seed (Salience Network)
 G-carriers < AA Superior Frontal R 18 54 22 191 3.85 <0.0001
Right dorsolateral prefrontal seed (Executive control network)
 G-carriers < AA Superior Frontal R 14 41 39 930 4.69 <0.0001
Superior Frontal R 17 44 27 s.c. 4.64 <0.0001
Superior Temporal pole R 36 12 -21 747 4.32 <0.0001
Superior Temporal pole R 38 12 -21 280 3.91 <0.0001
  1. SCN structural covariance network, DMN default mode network, s.c. same cluster