Associations of Bcl-2 rs956572 genotype groups in the structural covariance network in early-stage Alzheimer’s disease

Table 2 Correlation coefficients between seed volume and cognitive test scores

Seed region	R Entorhinal		L Posterior Cingulate		R Frontoinsular		R Dorsolateral prefrontal
MNI Coordinates	(25,-9,-28)		(-2,-36, 35)		(38, 26,-10)		(44, 36, 20)
Bcl-2 Genotypes	G-carriers	AA	G-carriers	AA	G-carriers	AA	G-carriers	AA
Seed Volume	0.782	0.786	0.642	0.671	0.647	0.645	0.474	0.447
MMSE	0.220	0.458 ^b	0.273 ^a	0.191	0.135	0.123	-0.056	0.571 ^b
T1 to T4 trial scores	0.216	0.298	0.211	0.123	0.133	0.248	0.124	0.559 ^b
30 second recalls	0.323 ^b	0.204	0.204	0.278	0.180	0.296	0.073	0.689 ^b
10 minute recalls	0.313 ^b	0.213	0.193	0.100	0.087	0.123	-0.038	0.484 ^b
Modified Rey-Osterrieth Recall	0.179	0.415 ^a	0.188	0.120	0.168	0.243	-0.034	0.478 ^a
Modified Rey-Osterrieth Copy	-0.006	0.192	0.136	0.081	-0.009	0.271	-0.123	0.505 ^b
Visual object and Space Perception	-0.037	-0.006	0.058	-0.087	0.096	-0.204	-0.093	0.144
Semantic fluency: Animal	0.298 ^a	-0.002	0.101	0.141	0.167	0.041	0.068	0.527 ^b
Boston Naming Test	0.114	0.016	0.149	0.209	0.060	0.170	0.106	0.459 ^a
Comprehension	0.079	-0.106	0.253	0.179	0.126	0.106	0.234	0.342
Digit backward	-0.013	-0.018	0.139	0.164	-0.048	0.171	-0.090	0.227
Stroop Interference Correct	0.381 ^b	0.259	0.209	0.363	0.398 ^b	-0.009	0.298 ^a	0.600 ^b
Design fluency	0.265 ^a	0.201	0.025	0.007	0.117	0.495 ^a	-0.079	0.618 ^b
Trail making test time	-0.162	-0.289	-0.168	-0.169	-0.048	-0.116	0.025	-0.516 ^b
Correct line in Trail making	0.192	0.062	0.227	-0.023	0.261 ^a	0.160	-0.047	0.497 ^b
Neuropsychiatric Inventory	-0.023	-0.037	-0.103	-0.253	0.008	-0.117	-0.047	0.063

Numbers indicate Spearman correlation coefficients, ^ap < 0.05; ^b p <0.01
MMSE Mini-Mental State Examination, MNI Montreal Neurological Institute, R right, L Left

ISSN: 1758-9193