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Fig. 1 | Alzheimer's Research & Therapy

Fig. 1

From: Novel botanical drug DA-9803 prevents deficits in Alzheimer’s mouse models

Fig. 1

Chronic treatment with DA-9803 restores behavioral deficits and decreases Aβ levels in cortices of 5XFAD mice. a, b Alternation behavior in a Y-maze before (a) and after (b) 4-week chronic DA-9803 treatment in 5-month-old 5XFAD mice (n = 5 mice/group). c Latency of entry into the dark compartment on a passive avoidance test after 4-week DA-9803 treatment (n = 5 mice/group). d, e Total Aβ40 (d) and Aβ42 (e) levels in cortices of 5XFAD mice after 4-week DA-9803 treatment (n = 5 mice/group). Mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001. n.s. not significant, Aβ amyloid-beta

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