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Fig. 6 | Alzheimer's Research & Therapy

Fig. 6

From: Diffusion kurtosis imaging allows the early detection and longitudinal follow-up of amyloid-β-induced pathology

Fig. 6

Region of interest-based histological correlation analysis. a Graphs showing the Pearson correlations between mean kurtosis (MK), axial kurtosis (AK), radial kurtosis (RK) and fractional anisotropy (FA) and percent optical density (%O.D.) of anti-amyloid-β (clone 4G8) antibody (4G8), glial fibrillary acidic protein (GFAP), ionised calcium-binding adapter molecule 1 (IBA1) and myelin basic protein (MBP). The graph includes data from the wild-type (WT) mice (triangles) and APP/PS1 mice (circles) at 2 months of age (grey), 4 months of age (green), 6 months of age (blue) and 8 months of age (red). b Pearson correlation values (r) and p values of these correlations between the different diffusion tensor and diffusion kurtosis metrics and the histological parameters

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