Fig. 7
3H-Deprenyl (3H-DED) competition with unlabeled THK5351 and T807. Competition binding studies using increasing concentrations of unlabeled THK5117 or unlabeled T807 (1.10−14 to 1.10−5 M) with 3H-DED in hippocampus (a) and putamen (b) brain homogenates of two Alzheimer’s disease (AD) cases. Error bars represent the SEM of two experiments in triplicate for two AD cases. K i Inhibition constant