Fig. 4From: Comparative binding properties of the tau PET tracers THK5117, THK5351, PBB3, and T807 in postmortem Alzheimer brainsCompetition binding assay with 3H-THK5351 and unlabeled THK5351, THK5117, and T807. Competition binding studies using 3H-THK5351 (1.5 nM) binding in postmortem hippocampus brain homogenates from three patients with Alzheimer’s disease using increasing concentrations of unlabeled THK5351, unlabeled THK5117, or unlabeled T807 (1.10−14 to 1.10−5 M). Error bars represent the SEM from three experiments in triplicates using two tissue samples for unlabeled THK5351 and THK5117 and three tissue samples for unlabeled T807. K i Inhibition constantBack to article page