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Fig. 1 | Alzheimer's Research & Therapy

Fig. 1

From: Oligomeric forms of amyloid-β protein in plasma as a potential blood-based biomarker for Alzheimer’s disease

Fig. 1

The Multimer Detection System concept. a Monomers are proteins with a single epitope that can be captured by an antibody (capturing antibody 6E10) attached to the surface of the plate. After the addition of a detection antibody (FF51-horseradish peroxidase [HRP]), monomer proteins cannot be detected, because the single epitope is already occupied. b Multimers with numerous epitopes can be detected by detection antibodies. The capturing and detection antibodies are different, but their epitopes overlap. ELISA Enzyme-linked immunosorbent assay

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