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Table 4 Results of the generalized estimating equation analyzing the effect of 2-year NPI agitation/aggression changes in ApoE4-positive patients with AD

From: The clinical significance of plasma clusterin and Aβ in the longitudinal follow-up of patients with Alzheimer’s disease

 

β

SE

95% CI

P value

Gender

 Male

0.16

2.25

(−4.25, 4.57)

0.94

 Female

Ref

   

Ratio of Aβ1–42/Aβ1–40

 High

6.06

2.48

(1.20, 10.62)

0.02

 Medium

1.20

2.24

(−3.18, 5.59)

0.59

 Low

Ref

   

Age

0.18

0.14

(−0.10, 0.46)

0.21

Education years

0.11

0.17

(−0.23, 0.45)

0.51

Time

−0.96

0.70

(−2.34, 0.42)

0.17

  1. Adjusted for age, education years, gender, and time
  2. amyloid beta peptide, AD Alzheimer’s disease, CI confidence interval, NPI Neuropsychiatric Inventory, SE standard error