Alzheimer's Research & Therapy

Table 3 Results of the generalized estimating equation analyzing the effect of 2-year MMSE changes in patients with AD

From: The clinical significance of plasma clusterin and Aβ in the longitudinal follow-up of patients with Alzheimer’s disease

	β	SE	95% CI	P value
Gender
Male	−0.32	0.83	(−1.95, 1.32)	0.71
Female	Referent
Clusterin level
High	−2.09	0.81	(−3.67, −0.51)	0.01
Medium	−0.87	0.71	(−2.27, 0.53)	0.22
Low	Referent
ApoE4 carrier
Positive	−2.75	0.69	(−4.11, −1.39)	0.00
Negative	Referent
Age	0.03	0.08	(−0.12, 0.17)	0.74
Education years	0.13	0.09	(−0.04, 0.30)	0.15
Time	−0.91	0.21	(−1.33, −0.49)	0.00

Adjusted for age, education years, gender, time, and ApoE4 carrier
Interaction in group*ApoE4 carrier: p value = 0.93 and group*time: p value = 0.21
AD Alzheimer’s disease, ApoE apolipoprotein E, CI confidence interval, MMSE Mini-Mental State Examination, SE standard error

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ISSN: 1758-9193

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