From: Dynamic changes of oligomeric amyloid β levels in plasma induced by spiked synthetic Aβ42
AD | Healthy normal control subjects | |
---|---|---|
Total sample number | 24 | 29 |
Sex | ||
Female | 13 (54.2%) | 16 (55.2%) |
Male | 11 (45.8%) | 13 (44.8%) |
Age, years (SD) | 67.6 (±7.4) | 62.4 (±5.7) |
Education, years (SD) | 13.1 (±3.9) | 13.2 (±3.5) |
CDR-SOB, mean | 6.35 | 0.03 |
MMSE score, mean | 17.7 | 29.03 |
ApoE ε4, % | 47.8 | 21.7 |
Note test | 1 | 0 |
Number of plasma samples | 24 | 29 |
CSF markers | 23 | 28 |
Aβ42, pg/ml, mean (SD) | 258.6 (±70.8) | 464.8 (±114.4) |
p-Tau, pg/ml, mean (SD) | 58.6 (±18.6) | 28.0 (±14.3) |
t-Tau, pg/ml, mean (SD) | 132.1 (±61.8) | 62.1 (±20.3) |
PiB-PET number | 23 | 28 |
Mean SUVR | 1.57 | 1.14 |
FDG-PET number | 18 | 28 |
Mean SUVR | 0.9 | 1.06 |