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Fig. 2 | Alzheimer's Research & Therapy

Fig. 2

From: Dynamic changes of oligomeric amyloid β levels in plasma induced by spiked synthetic Aβ42

Fig. 2

Changes of amyloid-β oligomers (AβOs) and amyloid-β (Aβ) monomers in pooled plasma of patients with Alzheimer’s disease (AD) and healthy normal control subjects. a After being spiked with different concentrations of Aβ42 in buffer vehicle, pooled AD plasma, and pooled healthy normal control plasma, oligomers were measured using a multimer detection system (MDS) at 0 h. b Pooled plasma samples were incubated at 37 °C after being spiked with 10 ng/ml Aβ42. Changes of Aβ42 levels at various time points were measured by MDS. Levels of Aβ40 (c) and Aβ42 (d) after being spiked with 10 ng/ml Aβ42 in pooled human plasma. Pooled plasma samples were incubated at 37 °C after 10 ng/ml Aβ42 were spiked. Data are mean ± SD. RLU Relative luminescence units. Arrow indicated no change in oligomer levels after an incubation period of 24 h

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