TY - JOUR AU - Stallard, Eric AU - Kinosian, Bruce AU - Stern, Yaakov PY - 2017 DA - 2017/09/20 TI - Personalized predictive modeling for patients with Alzheimer’s disease using an extension of Sullivan’s life table model JO - Alzheimer's Research & Therapy SP - 75 VL - 9 IS - 1 AB - Alzheimer’s disease (AD) progression varies substantially among patients, hindering calculation of residual total life expectancy (TLE) and its decomposition into disability-free life expectancy (DFLE) and disabled life expectancy (DLE) for individual patients with AD. The objective of the present study was to assess the accuracy of a new synthesis of Sullivan’s life table (SLT) and longitudinal Grade of Membership (L-GoM) models that estimates individualized TLEs, DFLEs, and DLEs for patients with AD. If sufficiently accurate, such information could enhance the quality of important decisions in AD treatment and patient care. SN - 1758-9193 UR - https://doi.org/10.1186/s13195-017-0302-6 DO - 10.1186/s13195-017-0302-6 ID - Stallard2017 ER -