|
RAVLT Total Learning scorea
|
RAVLT Delayed Free Recall scoreb
|
---|
|
β Coefficient
|
p Value
|
95% CI
|
β Coefficient
|
p Value
|
95% CI
|
---|
Amyloid PET positivity
|
−2.766
|
0.001
|
−4.321
|
−1.21
|
−1.056
|
0.001
|
−1.689
|
−0.422
|
Diagnosis
|
−5.586
|
<0.0001
|
−7.122
|
−4.05
|
−1.791
|
<0.0001
|
−2.404
|
−1.178
|
Sex
|
6.308
|
<0.0001
|
4.804
|
7.812
|
1.854
|
<0.0001
|
1.245
|
2.463
|
A+ × diagnosis × sex
|
−6.616
|
0.025
|
−12.385
|
−0.847
|
−2.116
|
0.073
|
−4.431
|
0.199
|
A+ × diagnosis
|
−1.486
|
0.314
|
−4.382
|
1.411
|
−0.536
|
0.359
|
−1.683
|
0.611
|
A+ × sex
|
0.229
|
0.877
|
−2.677
|
3.135
|
−0.623
|
0.288
|
−1.773
|
0.528
|
Diagnosis × sex
|
0.689
|
0.639
|
−2.19
|
3.567
|
−0.562
|
0.341
|
−1.717
|
0.594
|
Age
|
−0.371
|
<0.0001
|
−0.473
|
−0.268
|
−0.095
|
<0.0001
|
−0.137
|
−0.053
|
Education
|
0.388
|
0.003
|
0.134
|
0.643
|
0.114
|
0.035
|
0.008
|
0.221
|
Modified MoCA
|
1.357
|
<0.0001
|
1.002
|
1.711
|
0.404
|
<0.0001
|
0.279
|
0.53
|
APOE ε4 carrier status
|
−1.713
|
0.0259
|
−3.219
|
−0.207
|
−0.817
|
0.008
|
−1.424
|
−0.211
|
-
Abbreviations: A
+ Florbetapir positron emission tomography amyloid positivity, APOE Apolipoprotein E, MoCA Montreal Cognitive Assessment, PET Positron emission tomography, RAVLT Rey Auditory Verbal Learning
- Age, education, and modified MoCA score were centered at their means. Dichotomous variables were centered on zero (RAVLT total learning score overall model, R = 0.623, p < 0.0001; RAVLT Delayed Free Recall score overall model, R = 0.522, p < 0.0001)
-
a
n = 739 after exclusions
-
b
n = 741 after exclusions