Fig. 3
From: A coiled conformation of amyloid-β recognized by antibody C706
Superposition of β-amyloid (Aβ) residues 1–5 in the C706 complex on the 3D6 complex (1hix). Variable domains of the monoclonal antibodies are shown as tubes (variable domain of the light chain [VL] lighter than variable domain of the heavy chain [VH]), the Aβ peptides as sticks. C706 (blue) binds Aβ from the bottom, and 3D6 (orange) binds Aβ from the back of the figure. Aβ bound to C706 is shown in magenta, and Aβ bound to 3D6 is shown in yellow. Hydrogen bond Ala2-Arg5 in Aβ is shown as a dashed line