Table 1 Subjects’ clinical and demographic features

Age, years

71.4 (6.7)

74.9 (8.0)

75.7 (5.3)

74.1 (7.2)

2.4

Sex, F/M

15/15

15/26

8/17

11/8

χ² = 4.3

Handedness, L/R

3/27

0/41

0/25

0/19

–

Ethnicity, C/N

28/2

33/8

18/7

15/4

χ² = 4.4

CDR-SB

0.1 (0.2)

6.2 (2.2)^a

7.2 (2.9)^a

6.4 (2.5)^a

69.6^b

MMSE (maximum score 30)

28.2 (1.3)

16.8 (5.0)^a

15.6 (4.1)^a

17.4 (4.6) ^a

60.3^b

WMH visual rating

4.3 (2.3)

5.0 (1.3)

11.2 (4.5) ^a,c

9.2 (4.6) ^a,c

29.3^b

Patients with cognitive scores

AD (n = 33)

AD + CeVD (n = 20)

VaD (n = 16)

ANOVA (F test)

 Age

75.6 (7.6)

75.1 (5.7)

73.8 (8.4)

0.3

 Sex, F/M

12/21

7/13

10/6

χ² = 3.6

 Handedness L/R

0/33

0/29

0/16

–

 Ethnicity, C/N

25/8

14/6

13/3

χ² = 0.6

 CDR-SB

6.3 (2.4)

7.3 (2.9)

6.6 (2.6)

0.9

 MMSE (maximum score 30)

16.4 (5.2)

15.8 (4.5)

17.4 (4.4)

0.5

Visual construction

0.09 (1.0)

−0.08 (0.9)

−0.09 (1.1)

0.3

Visual motor

0.09 (1.1)

−0.08 (0.9)

−0.08 (1.0)

0.2

Attention

0.09 (1.1)

0.02 (0.8)

−0.21 (1.1)

0.5

Executive functioning

0.17 (1.1)

−0.18 (0.9)

−0.13 (1.0)

0.9

Language

0.09 (1.1)

−0.15 (0.9)

0 (0.9)

0.4

Verbal memory

−0.07 (1.1)

−0.22 (0.6)

0.42 (1.1)

2.0

Visuospatial memory

−0.09 (1.1)

−0.21 (0.8)

0.45 (1.1)

2.3