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Table 1 Subjects’ clinical and demographic features
| Groups | HC (n = 30) | AD (n = 41) | AD + CeVD (n = 25) | VaD (n = 19) | Overall ANOVA (F test) |
|---|---|---|---|---|---|
| Age, years | 71.4 (6.7) | 74.9 (8.0) | 75.7 (5.3) | 74.1 (7.2) | 2.4 |
| Sex, F/M | 15/15 | 15/26 | 8/17 | 11/8 | χ2 = 4.3 |
| Handedness, L/R | 3/27 | 0/41 | 0/25 | 0/19 | – |
| Ethnicity, C/N | 28/2 | 33/8 | 18/7 | 15/4 | χ2 = 4.4 |
| CDR-SB | 0.1 (0.2) | 6.2 (2.2)a | 7.2 (2.9)a | 6.4 (2.5)a | 69.6b |
| MMSE (maximum score 30) | 28.2 (1.3) | 16.8 (5.0)a | 15.6 (4.1)a | 17.4 (4.6) a | 60.3b |
| WMH visual rating | 4.3 (2.3) | 5.0 (1.3) | 11.2 (4.5) a,c | 9.2 (4.6) a,c | 29.3b |
| Patients with cognitive scores | AD (n = 33) | AD + CeVD (n = 20) | VaD (n = 16) | ANOVA (F test) | |
| Age | 75.6 (7.6) | 75.1 (5.7) | 73.8 (8.4) | 0.3 | |
| Sex, F/M | 12/21 | 7/13 | 10/6 | χ2 = 3.6 | |
| Handedness L/R | 0/33 | 0/29 | 0/16 | – | |
| Ethnicity, C/N | 25/8 | 14/6 | 13/3 | χ2 = 0.6 | |
| CDR-SB | 6.3 (2.4) | 7.3 (2.9) | 6.6 (2.6) | 0.9 | |
| MMSE (maximum score 30) | 16.4 (5.2) | 15.8 (4.5) | 17.4 (4.4) | 0.5 | |
| Visual construction | 0.09 (1.0) | −0.08 (0.9) | −0.09 (1.1) | 0.3 | |
| Visual motor | 0.09 (1.1) | −0.08 (0.9) | −0.08 (1.0) | 0.2 | |
| Attention | 0.09 (1.1) | 0.02 (0.8) | −0.21 (1.1) | 0.5 | |
| Executive functioning | 0.17 (1.1) | −0.18 (0.9) | −0.13 (1.0) | 0.9 | |
| Language | 0.09 (1.1) | −0.15 (0.9) | 0 (0.9) | 0.4 | |
| Verbal memory | −0.07 (1.1) | −0.22 (0.6) | 0.42 (1.1) | 2.0 | |
| Visuospatial memory | −0.09 (1.1) | −0.21 (0.8) | 0.45 (1.1) | 2.3 |
