|
Model Ia
|
Model IIb
|
Model IIIc
|
|---|
|
B
|
SE
|
t
|
p
|
B
|
SE
|
t
|
p
|
B
|
SE
|
t
|
p
|
|---|
|
AD-signature region CMglu
|
|
TSH
|
– 0.011
|
0.006
|
– 1.677
|
0.096
|
– 0.011
|
0.006
|
– 1.667
|
0.098
|
– 0.010
|
0.007
|
– 1.486
|
0.139
|
- Multiple linear regression analysis was conducted to investigate the relationship between serum TSH and AD-signature CMglu controlling for several variables
-
B regression coefficient, SE standard error, CMglu cerebral glucose metabolism, APOE apolipoprotein E, TSH thyroid-stimulating hormone, AD Alzheimer’s disease, Aβ amyloid beta protein
-
aAdjusted for age, gender, and APOE ε4 carrier status
-
bAdjusted for age, gender, APOE ε4 carrier status, and global Aβ retention (natural log-transformed)
-
cAdjusted for age, gender, APOE ε4 carrier status, global Aβ retention (natural log-transformed), and vascular risk score
