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Table 3 Multiple linear regression analysis with AD-signature CMglu as a dependent variable (n = 148)

From: Associations of thyroid hormone serum levels with in-vivo Alzheimer’s disease pathologies

Model Ia Model IIb Model IIIc
B SE t p B SE t p B SE t p
AD-signature region CMglu
TSH – 0.011 0.006 – 1.677 0.096 – 0.011 0.006 – 1.667 0.098 – 0.010 0.007 – 1.486 0.139
  1. Multiple linear regression analysis was conducted to investigate the relationship between serum TSH and AD-signature CMglu controlling for several variables
  2. B regression coefficient, SE standard error, CMglu cerebral glucose metabolism, APOE apolipoprotein E, TSH thyroid-stimulating hormone, AD Alzheimer’s disease, amyloid beta protein
  3. aAdjusted for age, gender, and APOE ε4 carrier status
  4. bAdjusted for age, gender, APOE ε4 carrier status, and global Aβ retention (natural log-transformed)
  5. cAdjusted for age, gender, APOE ε4 carrier status, global Aβ retention (natural log-transformed), and vascular risk score