| |
Intervention group, mean (SD)
|
Control group, mean (SD)
|
RM ANOVA group × time
|
|---|
|
Baseline
|
Follow-up
|
Baseline
|
Follow-up
|
F(1,68)
|
p
|
d
|
1 – β
|
|---|
|
NPI totala
|
22.5 (12.3)
|
10.3 (7.3)
|
22.5 (13.9)
|
16.2 (9.9)
|
4.4
|
0.04
|
0.51
|
0.99
|
|
Psychotic symptoms
|
3.3 (5.9)
|
1.0 (1.9)
|
2.8 (4.6)
|
1.9 (3.3)
|
1.6
|
0.22
|
0.30
|
0.70
|
|
Emotional symptoms
|
11.0 (7.3)
|
4.0 (4.2)
|
10.7 (9.0)
|
7.2 (5.9)
|
3.7
|
0.06
|
0.75
|
0.99
|
|
Behavior symptoms
|
6.9 (4.9)
|
4.0 (4.4)
|
6.1 (4.5)
|
5.2 (4.6)
|
4.6
|
0.04
|
0.52
|
0.99
|
|
Neurovegetative symptoms
|
1.3 (2.7)
|
1.3 (2.8)
|
2.9 (4.6)
|
1.9 (3.1)
|
0.8
|
0.39
|
0.21
|
0.41
|
|
CMAI totalb
|
51.4 (12.5)
|
41.7 (10.2)
|
51.3 (12.4)
|
45.5 (10.7)
|
2.6
|
0.11
|
0.40
|
0.90
|
|
Aggressive behavior
|
15.9 (5.1)
|
12.9 (1.8)
|
16.5 (5.8)
|
14.1 (2.9)
|
<0.1
|
0.57
|
0.42
|
0.21
|
|
Physically nonaggressive behavior
|
16.3 (7.4)
|
13.9 (7.5)
|
16.8 (6.1)
|
14.9 (6.7)
|
0.2
|
0.70
|
0.11
|
0.15
|
|
Verbally agitated behavior
|
11.3 (5.9)
|
7.4 (4.1)
|
9.7 (4.4)
|
8.8 (4.4)
|
7.9
|
0.01
|
0.68
|
0.99
|
|
Hiding and hoarding
|
2.3 (1.5)
|
2.4 (1.5)
|
2.7 (2.3)
|
2.3 (1.1)
|
2.3
|
0.33
|
0.24
|
0.50
|
- Number of patients: n = 35 in each group
-
CMAI Cohen-Mansfield Agitation Inventory, NPI Neuropsychiatric Inventory, d effect size (Cohen’s d), F F-ratio from ANOVA (between-group degrees of freedom, within-group degrees of freedom), p statistical significance, RM-ANOVA repeated-measures analysis of variance, 1 – β test power, SD standard deviation
-
aNPI range and scaling, 0–144 points (0 meaning no symptoms); dimensions: psychotic symptoms, 0–24 points (0 meaning no symptoms); emotional symptoms, 0–48 points (0 meaning no symptoms); behavior symptoms, 0–48 points (0 meaning no symptoms); neurovegetative symptoms, 0–24 points (0 meaning no symptoms)
-
bCMAI range and scaling, 29–203 points (29 meaning no symptoms); dimensions: aggressive behavior, 12–84 points (12 meaning no symptoms); physically nonaggressive behavior, 6–42 points (6 meaning no symptoms); verbally agitated behavior, 4–28 points (4 meaning no symptoms); hiding and hoarding, 2–14 points (2 meaning no symptoms)
