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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: RETRACTED ARTICLE: Increased Aβ42-α7-like nicotinic acetylcholine receptor complex level in lymphocytes is associated with apolipoprotein E4-driven Alzheimer’s disease pathogenesis

Fig. 3

ApoE fragments do not affect Aβ42-Aβ42 interaction in vitro. Biotin-tagged Aβ42 trapped streptavidin-coated 96-well plate was incubated with 0.1–100 μM apoE fragments for 10 min prior to the addition of 20 nM FITC-conjugated Aβ42. The level of Aβ42-Aβ42 complexes was measured by the residual FITC signals. The data are mean ± SEM of percentage change from vehicle-treated wells (n = 6). The apoE fragments did not alter the Aβ42-Aβ42 association. The dose-response curve for each peptide was analyzed using one-factor ANOVA. There is no statistical significance observed. ApoE apolipoprotein E

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