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Fig. 1 | Alzheimer's Research & Therapy

Fig. 1

From: Stem cell models of Alzheimer’s disease: progress and challenges

Fig. 1

Stem cell applications. Schematic to depict the potential applications of stem cell technology. Patient material is reprogrammed to iPSCs via the four reprogramming genes. Relevant advantages and disadvantages of the subsequent differentaition to cortical neurons via 2D and 3D methods are discussed. Finally, applications for stem cell-derived neurons are depicted, namely drug screening, investigating disease mechanisms, in vivo transplantation of neuronal material to model organisms as well as the potential for cell therapy

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