Skip to main content
Fig. 4 | Alzheimer's Research & Therapy

Fig. 4

From: A vaccine with Aβ oligomer-specific mimotope attenuates cognitive deficits and brain pathologies in transgenic mice with Alzheimer’s disease

Fig. 4

EBY100-L2 (AOE1) vaccination attenuated cognitive deficits in APP/PS1 transgenic mice. The cognitive function of Alzheimer’s disease (AD) mice was determined by novel object recognition (NOR) and Y-maze tests 2 weeks after the last vaccination. a Exploration times of mice for the old and new objects during NOR tests (compared with exploration times for old object, *p < 0.05). b Discrimination index of mice for the new object during the NOR test (compared with AD control, *p < 0.05). c and d Time spent in the new arm (c) and the entries into the new arm (d) of mice vaccinated with or without AOE1 vaccine (compared with AD control, *p < 0.05). WT Wild type

Back to article page

Alzheimer's Research & Therapy

ISSN: 1758-9193