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Table 1 Targeted MTM intervention: baseline participant characteristics

From: Optimizing medication appropriateness in older adults: a randomized clinical interventional trial to decrease anticholinergic burden

Demographics

All subjects (N = 50)

Control group (n = 25)

MTM group (n = 25)

p value

Age (years)

77.7 ± 6.6

79.1 ± 6.9

76.3 ± 6.2

0.13

Education (years)

16.1 ± 2.8

15.8 ± 3.0

16.5 ± 2.5

0.34

Female

35 (70.0)

17 (68.0)

18 (72.0)

0.76

Race

   

0.99

 White

45 (90.0)

22 (88.0)

23 (92.0)

 Black or African American

5 (10.0)

3 (12.0)

2 (8.0)

Clinical Dementia Rating

   

0.13

 0

33 (66.0)

13 (52.0)

20 (80.0)

 0.5

12 (24.0)

8 (32.0)

4 (16.0)

 1.0

5 (10.0)

4 (16.0)

1 (4.0)

Anticholinergic medication use

 Medication appropriateness index

12.6 ± 6.3

13.0 ± 4.4

12.2 ± 7.9

0.63

 Anticholinergic drug scale

2.8 ± 1.6

2.9 ± 1.3

2.8 ± 1.9

0.73

 Number of anticholinergic drugs

  1

25 (50.0)

11 (44.0)

14 (56.0)

0.40

  ≥2

25 (50.0)

14 (56.0)

11 (44.0)

 

 Used anticholinergic drugs with moderate/strong activity

31 (62)

18 (72)

13 (52)

0.14

RAND SF-36

 Health domains

  General health

67.7 ± 17.9

69.4 ± 14.8

66.0 ± 20.7

0.52

  Physical functioning

67.4 ± 25.6

60.4 ± 25.9

74.2 ± 23.9

0.06

  Bodily pain

66.6 ± 28.1

63.1 ± 25.8

70.0 ± 30.4

0.40

  Role limitations, physical

53.1 ± 38.8

50.0 ± 33.8

56.3 ± 43.8

0.58

  Mental health

82.6 ± 13.0

87.1 ± 9.4

78.2 ± 14.6

0.02

  Vitality

56.1 ± 23.2

57.3 ± 23.2

55.0 ± 23.7

0.73

  Social functioning

80.1 ± 22.7

80.7 ± 23.0

79.5 ± 22.8

0.85

  Role limitation, emotional

81.3 ± 29.9

84.7 ± 21.9

77.8 ± 36.3

0.43

 Component scores

  Physical health

63.8 ± 22.5

60.7 ± 19.1

66.8 ± 25.3

0.35

  Mental health

75.0 ± 17.8

77.5 ± 13.6

72.7 ± 21.0

0.35

  1. Data presented as mean ± SD or N (%)
  2. MTM medication therapy management, SF-36 Short Form Health Survey