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Table 1 Targeted MTM intervention: baseline participant characteristics

From: Optimizing medication appropriateness in older adults: a randomized clinical interventional trial to decrease anticholinergic burden

Demographics All subjects (N = 50) Control group (n = 25) MTM group (n = 25) p value
Age (years) 77.7 ± 6.6 79.1 ± 6.9 76.3 ± 6.2 0.13
Education (years) 16.1 ± 2.8 15.8 ± 3.0 16.5 ± 2.5 0.34
Female 35 (70.0) 17 (68.0) 18 (72.0) 0.76
Race     0.99
 White 45 (90.0) 22 (88.0) 23 (92.0)
 Black or African American 5 (10.0) 3 (12.0) 2 (8.0)
Clinical Dementia Rating     0.13
 0 33 (66.0) 13 (52.0) 20 (80.0)
 0.5 12 (24.0) 8 (32.0) 4 (16.0)
 1.0 5 (10.0) 4 (16.0) 1 (4.0)
Anticholinergic medication use
 Medication appropriateness index 12.6 ± 6.3 13.0 ± 4.4 12.2 ± 7.9 0.63
 Anticholinergic drug scale 2.8 ± 1.6 2.9 ± 1.3 2.8 ± 1.9 0.73
 Number of anticholinergic drugs
  1 25 (50.0) 11 (44.0) 14 (56.0) 0.40
  ≥2 25 (50.0) 14 (56.0) 11 (44.0)  
 Used anticholinergic drugs with moderate/strong activity 31 (62) 18 (72) 13 (52) 0.14
RAND SF-36
 Health domains
  General health 67.7 ± 17.9 69.4 ± 14.8 66.0 ± 20.7 0.52
  Physical functioning 67.4 ± 25.6 60.4 ± 25.9 74.2 ± 23.9 0.06
  Bodily pain 66.6 ± 28.1 63.1 ± 25.8 70.0 ± 30.4 0.40
  Role limitations, physical 53.1 ± 38.8 50.0 ± 33.8 56.3 ± 43.8 0.58
  Mental health 82.6 ± 13.0 87.1 ± 9.4 78.2 ± 14.6 0.02
  Vitality 56.1 ± 23.2 57.3 ± 23.2 55.0 ± 23.7 0.73
  Social functioning 80.1 ± 22.7 80.7 ± 23.0 79.5 ± 22.8 0.85
  Role limitation, emotional 81.3 ± 29.9 84.7 ± 21.9 77.8 ± 36.3 0.43
 Component scores
  Physical health 63.8 ± 22.5 60.7 ± 19.1 66.8 ± 25.3 0.35
  Mental health 75.0 ± 17.8 77.5 ± 13.6 72.7 ± 21.0 0.35
  1. Data presented as mean ± SD or N (%)
  2. MTM medication therapy management, SF-36 Short Form Health Survey