TY - JOUR AU - Chiu, Wang Zheng AU - Donker Kaat, Laura AU - Boon, Agnita J. W. AU - Kamphorst, Wouter AU - Schleicher, Axel AU - Zilles, Karl AU - van Swieten, John C. AU - Palomero-Gallagher, Nicola PY - 2017 DA - 2017/04/17 TI - Multireceptor fingerprints in progressive supranuclear palsy JO - Alzheimer's Research & Therapy SP - 28 VL - 9 IS - 1 AB - Progressive supranuclear palsy (PSP) with a frontal presentation, characterized by cognitive deficits and behavioral changes, has been recognized as an early clinical picture, distinct from the classical so-called Richardson and parkinsonism presentations. The midcingulate cortex is associated with executive and attention tasks and has consistently been found to be impaired in imaging studies of patients with PSP. The aim of the present study was to determine alterations in neurotransmission underlying the pathophysiology of PSP, as well as their significance for clinically identifiable PSP subgroups. SN - 1758-9193 UR - https://doi.org/10.1186/s13195-017-0259-5 DO - 10.1186/s13195-017-0259-5 ID - Chiu2017 ER -