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Table 2 Spearman’s rank correlation results of plasma and CSF insulin with CSF markers of AD pathology

From: The influence of insulin resistance on cerebrospinal fluid and plasma biomarkers of Alzheimer’s pathology

 

CSF Aβ/tau

CSF Aβ

CSF T-tau

CSF P-tau

P-insulin (LIAISON)

Coefficient

−0.302

0.182

0.310

0.249

Significance

0.021*

0.172

0.018*

0.060

P-insulin (ELISA)

Coefficient

−0.277

0.183

0.299

0.224

Significance

0.035*

0.169

0.023*

0.091

CSF insulin (ELISA)

Coefficient

0.039

0.098

−0.002

−0.111

Significance

0.771

0.466

0.990

0.406

  1. CSF cerebrospinal fluid, AD Alzheimer’s disease, Aβ amyloid beta, T-tau total tau, P-tau tau phosphorylated at the Thr181 epitope, ELISA enzyme-linked immunosorbent assay
  2. *Significant at p < 0.05
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Alzheimer's Research & Therapy

ISSN: 1758-9193