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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: Evaluation of a DNA Aβ42 vaccine in adult rhesus monkeys (Macaca mulatta): antibody kinetics and immune profile after intradermal immunization with full-length DNA Aβ42 trimer

Fig. 3

Antibody production in rhesus macaques after the different DNA amyloid-β peptide 1–42 (Aβ42) immunization time points. a Anti-Aβ42 antibody levels in DNA Aβ42-immunized rhesus monkeys (n = 6) are shown for blood drawn prior to the immunizations, from blood of animals immunized three, four, five, and six times, and from blood drawn following a 3-month rest period. b Antibody levels in animals that had received the high dose (16 μg of DNA per immunization time point, black bar) or the low dose (8 μg of DNA per immunization time point, gray bar) did not differ significantly following the sixth immunization time point. c Antibody levels declined slightly with the 3-month rest period

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