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Fig. 11 | Alzheimer's Research & Therapy

Fig. 11

From: Evaluation of a DNA Aβ42 vaccine in adult rhesus monkeys (Macaca mulatta): antibody kinetics and immune profile after intradermal immunization with full-length DNA Aβ42 trimer

Fig. 11

Antibodies from DNA amyloid-β peptide 1–42 (Aβ42)-immunized monkeys stain amyloid plaques containing human Aβ42 peptides in brain sections of triple-transgenic Alzheimer’s disease (3xTg-AD) mice. a Plaque staining in hippocampal area of 3xTg-AD mouse with plasma from animal 28282. b Control staining in parallel section with commercial anti-Aβ42 antibody (6E10). c No staining in parallel section that was incubated with the secondary antibody and detection reagents only. Scale bar indicates 100 μm

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