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Table 2 Baseline neuropsychological data

From: Memory is preserved in older adults taking AT1 receptor blockers

Neuropsychological test Total (n = 1586) Normotensive (n = 782) HTN-ARBs (n = 183) HTN-Other (n = 621) F-Value p Value
Memory
 LM Immediate Recall 10.6 (4.3) 10.7 (4.4) 10.9 (4.3) 10.4 (4.2) 0.269 0.764
 LM Delayed Recall 8.5 (5.0) 8.6 (5.1) 9.2 (5.0) 8.3 (4.8) 1.987 0.137
 RAVLT Immediate Recall 38.2 (11.6) 39.6 (11.8) 38.1 (11.8) 36.5 (11.1) 4.986 0.007
 RAVLT Delayed Recall 5.3 (4.3) 5.8 (4.4) 5.5 (4.4) 4.5 (3.9) 9.642 <0.001
 RAVLT Recognition 11.4 (3.3) 11.7 (3.2) 11.7 (3.1) 11.0 (3.5) 5.692 0.003
Attention/executive function
 Digit Span forward score 8.4 (2.0) 8.5 (1.9) 8.1 (2.2) 8.4 (2.1) 1.100 0.402
 Digit Span forward span 6.6 (1.1) 6.7 (1.0) 6.5 (1.1) 6.6 (1.1) 0.953 0.386
 Digit Span backward score 6.5 (2.1) 6.6 (2.2) 6.5 (2.1) 6.4 (2.1) 0.121 0.886
 Digit Span backward span 4.8 (1.2) 4.8 (1.2) 4.7 (1.1) 4.7 (1.2) 0.021 0.979
 Trail Making Test A scorea 1.56 (0.16) 1.53 (0.15) 1.58 (0.16) 1.58 (0.16) 8.363 <0.001
 Trail Making Test B scorea 1.97 (0.21) 1.94 (0.21) 1.98 (0.20) 2.00 (0.21) 3.900 0.020
Language
 Animal Fluency 18.4 (5.5) 18.7 (5.4) 18.4 (5.3) 18.0 (5.7) 0.173 0.841
 Vegetable Fluency 12.2 (4.1) 12.3 (3.9) 12.2 (4.2) 12.1 (4.3) 0.206 0.814
 BNTa 0.48 (0.33) 0.47 (0.33) 0.47 (0.33) 0.51 (0.33) 1.385 0.251
  1. Abbreviations: BNT Boston Naming Test, HTN-ARBs Participants who took angiotensin II receptor blockers, HTN-Other Participants who took other antihypertensive drugs that were not angiotensin II receptor blockers, LM Logical Memory, RAVLT Rey Auditory Verbal Learning Test
  2. Data are summarized as mean (SD), unless otherwise indicated. All scores were corrected for age, sex, education level, BMI, and apolipoprotein ε4 allele carrier status. Significant differences (p < 0.05) among medication groups are indicated by boldface type
  3. aScores were log-transformed and are presented to two decimal places