Fig. 5
From: Monoamine oxidase B inhibitor, selegiline, reduces 18F-THK5351 uptake in the human brain
18F-THK5351 autoradiography competition with R-(–)-deprenyl hydrochloride shows dose-dependent uptake decline. a In vitro autoradiography of the postmortem striatum, prefrontal cortex, and hippocampal brain sections of Alzheimer’s disease (AD) patients and controls showing the reduction of baseline 18F-THK5351 binding after 150 nM and 500 nM R-(–)-deprenyl hydrochloride challenge. b Reduction of percentage of 18F-THK5351 total uptake is greater in the striatum than in the prefrontal cortex and hippocampus