DSM-5 mild neurocognitive disorder | IWG MCI | ||||
---|---|---|---|---|---|
Criteria | Algorithm | Criteria | Algorithm | ||
A. Both of the following: | |||||
A1 | Concern of self or informant of significant cognitive decline in one or more cognitive domains | MAC-Q >24 or IQCODE >3.31 or recent doctor’s consultation about cognitive change or informant reported worsening of everyday cognitive functiona | 1 | Participant is not normal and not demented | Does not meet criteria for DSM-IV dementia or DSM-5 major NCD and all cognitive domains not in normal range (z score ≤ –1.0) |
A2 | Modest impairment in cognitive performance in one or more cognitive domains | Mean z score for one or more of the following domains is > –2.0 to ≤ –1.0: complex attention, executive function, learning and memory, language, perceptual/motor, social cognition, or mean decline in performance between waves 3 and 4 that is > –2.0 to ≤ –1.0 SD below norms on select testsb | 2. Either or both of the following (2a and/or 2b): | ||
2a | Self and/or informant report of cognitive decline and Impairment on objective cognitive tasks | MAC-Q >24 or IQCODE >3.31 or recent doctor’s consultation about cognitive change or informant reported worsening in everyday cognition. And mean z score ≥ –2.0 and ≤ –1.0 for one or more of: memory, complex attention, executive function, language, and perceptual/motor | |||
B | A1 and A2 do not interfere with capacity for independence in everyday life | No HRS-IADLc problems due to memory, or self-reported need for household/personal care help, or Bayer IADL <3.12, and (if A2 social cognition impaired, then no informant-reportedd change in social behaviors or emotion recognition) | 2b | Evidence of decline over time on objective cognitive tasks | Mean decline in performance between waves 3 and 4 that is > –2.0 to ≤ –1.0 SD below norms on select testsb |
C | The cognitive deficits do not occur exclusively in the context of a delirium | Informant reports deficits started 6 months or more ago, or informant-reported delirium signs present for less than duration of cognitive change | 3 | Preserved basic activities of daily living or minimal impairment on complex IADLs | No difficulty with Bayer IADL items 2, 4, and 11 or no self-reported need for personal care help, or Bayer IADL <3.12 |
D | The cognitive deficits are not better explained by another mental disorder | PHQ-9 < 10 and no informant-reported history of schizophrenia or other psychosis |